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Ribociclib Impurity 7

SZ CAT No SZ-R035014
CAS No NA
Mol.F. C23H30N8O2 : 1.5H2O
Mol.Wt. 450.5 : 1.5(18.0)
Inv. Status Out of Stock
Rel. CAS No 2470164-21-5 (Free base)


Chemical Name: 1-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide sesquihydrate

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.