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Pharmaceutical Reference Standards

Ribociclib

Picture of Ribociclib
CAT No: SZ-R035001
CAS No: 1211441-98-3
Mol.F. : C23H30N8O
Mol.Wt. : 434.6
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)
SZ-R035001
CAS No:1211441-98-3
Mol.F.: C23H30N8O
Mol.Wt.: 434.6
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib Succinate

Picture of Ribociclib Succinate
CAT No: SZ-R035002
CAS No: 1374639-75-4
Mol.F. : C23H30N8O : C4H6O4
Mol.Wt. : 434.6 : 118.1
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1211441-98-3 (free base)
SZ-R035002
CAS No:1374639-75-4
Mol.F.: C23H30N8O : C4H6O4
Mol.Wt.: 434.6 : 118.1
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1211441-98-3 (free base)

Ribociclib HCl

Picture of Ribociclib HCl
CAT No: SZ-R035003
CAS No: 1211443-80-9
Mol.F. : C23H30N8O : HCl
Mol.Wt. : 434.5 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1211441-98-3 (free base) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)
SZ-R035003
CAS No:1211443-80-9
Mol.F.: C23H30N8O : HCl
Mol.Wt.: 434.5 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1211441-98-3 (free base) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib N-Desmethyl Metabolite

Picture of Ribociclib N-Desmethyl Metabolite
CAT No: SZ-R035004
CAS No: NA
Mol.F. : C22H28N8O : HCl
Mol.Wt. : 420.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 1211441-59-6 (Free base)
SZ-R035004
CAS No:NA
Mol.F.: C22H28N8O : HCl
Mol.Wt.: 420.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 1211441-59-6 (Free base)

Ribociclib N,N-DiDesmethyl Metabolite

Picture of Ribociclib N,N-DiDesmethyl Metabolite
CAT No: SZ-R035005
CAS No: NA
Mol.F. : C21H26N8O
Mol.Wt. : 406.0
Inv. Status: Custom Synthesis
SZ-R035005
CAS No:NA
Mol.F.: C21H26N8O
Mol.Wt.: 406.0
Inv. Status: Custom Synthesis

Ribociclib Chloro Amide Impurity

Picture of Ribociclib Chloro Amide Impurity
CAT No: SZ-R035006
CAS No: 1211443-61-6
Mol.F. : C14H17ClN4O
Mol.Wt. : 292.8
Inv. Status: In Stock
SZ-R035006
CAS No:1211443-61-6
Mol.F.: C14H17ClN4O
Mol.Wt.: 292.8
Inv. Status: In Stock

Ribociclib Chloro Hydroxy Impurity

Picture of Ribociclib Chloro Hydroxy Impurity
CAT No: SZ-R035007
CAS No: 1374639-77-6
Mol.F. : C12H14ClN3O
Mol.Wt. : 251.7
Inv. Status: In Stock
SZ-R035007
CAS No:1374639-77-6
Mol.F.: C12H14ClN3O
Mol.Wt.: 251.7
Inv. Status: In Stock

Ribociclib Impurity 1

Picture of Ribociclib Impurity 1
CAT No: SZ-R035008
CAS No: NA
Mol.F. : C21H25N7O2 : 2(HCl)
Mol.Wt. : 407.5 : 2(36.5)
Inv. Status: In Stock
SZ-R035008
CAS No:NA
Mol.F.: C21H25N7O2 : 2(HCl)
Mol.Wt.: 407.5 : 2(36.5)
Inv. Status: In Stock

Ribociclib Impurity 2

Picture of Ribociclib Impurity 2
CAT No: SZ-R035009
CAS No: NA
Mol.F. : C23H30N8O2 : HCl
Mol.Wt. : 450.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 2069953-39-3 (Free base)
SZ-R035009
CAS No:NA
Mol.F.: C23H30N8O2 : HCl
Mol.Wt.: 450.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 2069953-39-3 (Free base)

Ribociclib Impurity 3

Picture of Ribociclib Impurity 3
CAT No: SZ-R035010
CAS No: NA
Mol.F. : C14H18N4O2
Mol.Wt. : 274.3
Inv. Status: Out of Stock
SZ-R035010
CAS No:NA
Mol.F.: C14H18N4O2
Mol.Wt.: 274.3
Inv. Status: Out of Stock

Ribociclib Impurity 4

Picture of Ribociclib Impurity 4
CAT No: SZ-R035011
CAS No: NA
Mol.F. : C27H34N8O4
Mol.Wt. : 534.6
Inv. Status: In Stock
SZ-R035011
CAS No:NA
Mol.F.: C27H34N8O4
Mol.Wt.: 534.6
Inv. Status: In Stock

Ribociclib Impurity 5

Picture of Ribociclib Impurity 5
CAT No: SZ-R035012
CAS No: NA
Mol.F. : C21H25N7O3 : 2HCl
Mol.Wt. : 423.5 : 2(36.5)
Inv. Status: Out of Stock, Under Synthesis
SZ-R035012
CAS No:NA
Mol.F.: C21H25N7O3 : 2HCl
Mol.Wt.: 423.5 : 2(36.5)
Inv. Status: Out of Stock, Under Synthesis

Ribociclib N-Oxide

Picture of Ribociclib N-Oxide
CAT No: SZ-R035013
CAS No: 2514753-27-4
Mol.F. : C23H30N8O2
Mol.Wt. : 450.5
Inv. Status: Under Synthesis
SZ-R035013
CAS No:2514753-27-4
Mol.F.: C23H30N8O2
Mol.Wt.: 450.5
Inv. Status: Under Synthesis

Ribociclib Impurity 7

Picture of Ribociclib Impurity 7
CAT No: SZ-R035014
CAS No: NA
Mol.F. : C23H30N8O2 : 1/2(H2O)
Mol.Wt. : 450.5 : 1/2(18.0)
Inv. Status: Out of Stock
Rel. CAS No : 2470164-21-5 (Free base)
SZ-R035014
CAS No:NA
Mol.F.: C23H30N8O2 : 1/2(H2O)
Mol.Wt.: 450.5 : 1/2(18.0)
Inv. Status: Out of Stock
Rel. CAS No : 2470164-21-5 (Free base)

N-Formyl Ribociclib

Picture of N-Formyl Ribociclib
CAT No: SZ-R035015
CAS No: NA
Mol.F. : C24H30N8O2 : HCl
Mol.Wt. : 462.6 : 36.5
Inv. Status: In Stock
SZ-R035015
CAS No:NA
Mol.F.: C24H30N8O2 : HCl
Mol.Wt.: 462.6 : 36.5
Inv. Status: In Stock

Ribociclib Impurity 8

Picture of Ribociclib Impurity 8
CAT No: SZ-R035016
CAS No: 1374639-76-5
Mol.F. : C12H14ClN3O
Mol.Wt. : 251.7
Inv. Status: In Stock
SZ-R035016
CAS No:1374639-76-5
Mol.F.: C12H14ClN3O
Mol.Wt.: 251.7
Inv. Status: In Stock

Ribociclib Impurity 9

Picture of Ribociclib Impurity 9
CAT No: SZ-R035017
CAS No: 1211443-55-8
Mol.F. : C12H12ClN3O
Mol.Wt. : 249.7
Inv. Status: In Stock
SZ-R035017
CAS No:1211443-55-8
Mol.F.: C12H12ClN3O
Mol.Wt.: 249.7
Inv. Status: In Stock

Ribociclib Impurity 10

Picture of Ribociclib Impurity 10
CAT No: SZ-R035018
CAS No: NA
Mol.F. : C23H30N8O2 : 2(HCl)
Mol.Wt. : 450.5 : 2(36.5)
Inv. Status: Out of Stock, Under Synthesis
SZ-R035018
CAS No:NA
Mol.F.: C23H30N8O2 : 2(HCl)
Mol.Wt.: 450.5 : 2(36.5)
Inv. Status: Out of Stock, Under Synthesis

Ribociclib Hydrobromide

Picture of Ribociclib Hydrobromide
CAT No: SZ-R035019
CAS No: 2209917-73-5
Mol.F. : C23H30N8O : HBr
Mol.Wt. : 434.6 : 80.9
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 1211441-98-3 (free base) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)
SZ-R035019
CAS No:2209917-73-5
Mol.F.: C23H30N8O : HBr
Mol.Wt.: 434.6 : 80.9
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 1211441-98-3 (free base) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib Sulfate

Picture of Ribociclib Sulfate
CAT No: SZ-R035020
CAS No: 2209917-76-8
Mol.F. : C23H30N8O : H2SO4
Mol.Wt. : 434.6 : 98.1
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 1211441-98-3 (free base) ; 1374639-75-4 (Succinate)
SZ-R035020
CAS No:2209917-76-8
Mol.F.: C23H30N8O : H2SO4
Mol.Wt.: 434.6 : 98.1
Inv. Status: Custom Synthesis
Rel. CAS No : 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 1211441-98-3 (free base) ; 1374639-75-4 (Succinate)

Ribociclib N-Desmethyl Metabolite Free base

Picture of Ribociclib N-Desmethyl Metabolite Free base
CAT No: SZ-R035021
CAS No: 1211441-59-6
Mol.F. : C22H28N8O
Mol.Wt. : 420.5
Inv. Status: Custom Synthesis
SZ-R035021
CAS No:1211441-59-6
Mol.F.: C22H28N8O
Mol.Wt.: 420.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 11

Picture of Ribociclib Impurity 11
CAT No: SZ-R035025
CAS No: NA
Mol.F. : C23H30N8O3
Mol.Wt. : 466.5
Inv. Status: Custom Synthesis
SZ-R035025
CAS No:NA
Mol.F.: C23H30N8O3
Mol.Wt.: 466.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 12

Picture of Ribociclib Impurity 12
CAT No: SZ-R035026
CAS No: 2460738-27-4
Mol.F. : C21H28N8O
Mol.Wt. : 408.5
Inv. Status: Custom Synthesis
SZ-R035026
CAS No:2460738-27-4
Mol.F.: C21H28N8O
Mol.Wt.: 408.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 13

Picture of Ribociclib Impurity 13
CAT No: SZ-R035027
CAS No: 2460734-07-8
Mol.F. : C23H30N8O2
Mol.Wt. : 450.5
Inv. Status: Custom Synthesis
SZ-R035027
CAS No:2460734-07-8
Mol.F.: C23H30N8O2
Mol.Wt.: 450.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 14

Picture of Ribociclib Impurity 14
CAT No: SZ-R035028
CAS No: NA
Mol.F. : C23H30N8O2
Mol.Wt. : 450.5
Inv. Status: Custom Synthesis
SZ-R035028
CAS No:NA
Mol.F.: C23H30N8O2
Mol.Wt.: 450.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 15

Picture of Ribociclib Impurity 15
CAT No: SZ-R035029
CAS No: 2460732-08-3
Mol.F. : C24H30N8O2
Mol.Wt. : 462.6
Inv. Status: Custom Synthesis
SZ-R035029
CAS No:2460732-08-3
Mol.F.: C24H30N8O2
Mol.Wt.: 462.6
Inv. Status: Custom Synthesis

Ribociclib Impurity 16

Picture of Ribociclib Impurity 16
CAT No: SZ-R035030
CAS No: NA
Mol.F. : C22H28N8O2
Mol.Wt. : 436.5
Inv. Status: Custom Synthesis
SZ-R035030
CAS No:NA
Mol.F.: C22H28N8O2
Mol.Wt.: 436.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 17

Picture of Ribociclib Impurity 17
CAT No: SZ-R035031
CAS No: NA
Mol.F. : C22H27N7O2
Mol.Wt. : 421.5
Inv. Status: Custom Synthesis
SZ-R035031
CAS No:NA
Mol.F.: C22H27N7O2
Mol.Wt.: 421.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 18

Picture of Ribociclib Impurity 18
CAT No: SZ-R035032
CAS No: 1823404-28-9
Mol.F. : C9H11BrClN3
Mol.Wt. : 276.6
Inv. Status: Custom Synthesis
SZ-R035032
CAS No:1823404-28-9
Mol.F.: C9H11BrClN3
Mol.Wt.: 276.6
Inv. Status: Custom Synthesis

Ribociclib Impurity 19

Picture of Ribociclib Impurity 19
CAT No: SZ-R035033
CAS No: 1214279-37-4
Mol.F. : C9H11Cl2N3
Mol.Wt. : 232.1
Inv. Status: Custom Synthesis
SZ-R035033
CAS No:1214279-37-4
Mol.F.: C9H11Cl2N3
Mol.Wt.: 232.1
Inv. Status: Custom Synthesis

Ribociclib Impurity 20

Picture of Ribociclib Impurity 20
CAT No: SZ-R035034
CAS No: 2481084-18-6
Mol.F. : C9H11Br2N3
Mol.Wt. : 321.0
Inv. Status: Custom Synthesis
SZ-R035034
CAS No:2481084-18-6
Mol.F.: C9H11Br2N3
Mol.Wt.: 321.0
Inv. Status: Custom Synthesis

Ribociclib Impurity 21

Picture of Ribociclib Impurity 21
CAT No: SZ-R035035
CAS No: NA
Mol.F. : C26H30ClN7O2
Mol.Wt. : 508.0
Inv. Status: Custom Synthesis
SZ-R035035
CAS No:NA
Mol.F.: C26H30ClN7O2
Mol.Wt.: 508.0
Inv. Status: Custom Synthesis

Ribociclib Impurity 22

Picture of Ribociclib Impurity 22
CAT No: SZ-R035036
CAS No: NA
Mol.F. : C24H27ClN6O2
Mol.Wt. : 467.0
Inv. Status: Custom Synthesis
SZ-R035036
CAS No:NA
Mol.F.: C24H27ClN6O2
Mol.Wt.: 467.0
Inv. Status: Custom Synthesis

Ribociclib Impurity 23

Picture of Ribociclib Impurity 23
CAT No: SZ-R035037
CAS No: NA
Mol.F. : C15H17N3O2
Mol.Wt. : 271.3
Inv. Status: Custom Synthesis
SZ-R035037
CAS No:NA
Mol.F.: C15H17N3O2
Mol.Wt.: 271.3
Inv. Status: Custom Synthesis

Ribociclib Impurity 24

Picture of Ribociclib Impurity 24
CAT No: SZ-R035038
CAS No: NA
Mol.F. : C24H27ClN6O2
Mol.Wt. : 467.0
Inv. Status: Custom Synthesis
SZ-R035038
CAS No:NA
Mol.F.: C24H27ClN6O2
Mol.Wt.: 467.0
Inv. Status: Custom Synthesis

Ribociclib Impurity 25

Picture of Ribociclib Impurity 25
CAT No: SZ-R035039
CAS No: NA
Mol.F. : C24H27ClN6O2
Mol.Wt. : 467.0
Inv. Status: Custom Synthesis
SZ-R035039
CAS No:NA
Mol.F.: C24H27ClN6O2
Mol.Wt.: 467.0
Inv. Status: Custom Synthesis

Ribociclib Impurity 26

Picture of Ribociclib Impurity 26
CAT No: SZ-R035040
CAS No: NA
Mol.F. : C10H6Cl2N4O
Mol.Wt. : 269.1
Inv. Status: Custom Synthesis
SZ-R035040
CAS No:NA
Mol.F.: C10H6Cl2N4O
Mol.Wt.: 269.1
Inv. Status: Custom Synthesis

Ribociclib Impurity 27

Picture of Ribociclib Impurity 27
CAT No: SZ-R035041
CAS No: 1298101-40-2
Mol.F. : C4HBr3N2
Mol.Wt. : 316.8
Inv. Status: Custom Synthesis
SZ-R035041
CAS No:1298101-40-2
Mol.F.: C4HBr3N2
Mol.Wt.: 316.8
Inv. Status: Custom Synthesis

Ribociclib Impurity 28

Picture of Ribociclib Impurity 28
CAT No: SZ-R035042
CAS No: 733039-20-8
Mol.F. : C9H11BrClN3
Mol.Wt. : 276.6
Inv. Status: Custom Synthesis
SZ-R035042
CAS No:733039-20-8
Mol.F.: C9H11BrClN3
Mol.Wt.: 276.6
Inv. Status: Custom Synthesis

Ribociclib Impurity 29

Picture of Ribociclib Impurity 29
CAT No: SZ-R035043
CAS No: NA
Mol.F. : C21H27N7O
Mol.Wt. : 393.5
Inv. Status: Custom Synthesis
SZ-R035043
CAS No:NA
Mol.F.: C21H27N7O
Mol.Wt.: 393.5
Inv. Status: Custom Synthesis

Ribociclib Impurity 30

Picture of Ribociclib Impurity 30
CAT No: SZ-R035044
CAS No: 36082-50-5
Mol.F. : C4HBrCl2N2
Mol.Wt. : 227.9
Inv. Status: Custom Synthesis
SZ-R035044
CAS No:36082-50-5
Mol.F.: C4HBrCl2N2
Mol.Wt.: 227.9
Inv. Status: Custom Synthesis

Stable Isotopes And Metabolites

Ribociclib-d6

Picture of Ribociclib-d6
CAT No: SZ-R035D01
CAS No: 1328934-40-2
Mol.F. : C23H24D6N8O
Mol.Wt. : 440.6
Inv. Status: In Stock
SZ-R035D01
CAS No:1328934-40-2
Mol.F.: C23H24D6N8O
Mol.Wt.: 440.6
Inv. Status: In Stock

Ribociclib-d8

Picture of Ribociclib-d8
CAT No: SZ-R035D02
CAS No: 2167898-24-8
Mol.F. : C23H22D8N8O
Mol.Wt. : 442.6
Inv. Status: Custom Synthesis
SZ-R035D02
CAS No:2167898-24-8
Mol.F.: C23H22D8N8O
Mol.Wt.: 442.6
Inv. Status: Custom Synthesis

Possible Nitroso Standards

Ribociclib Nitroso Impurity 1

Picture of Ribociclib Nitroso Impurity 1
CAT No: SZ-R035022
CAS No: NA
Mol.F. : C23H29N9O2
Mol.Wt. : 463.5
Inv. Status: In Stock
SZ-R035022
CAS No:NA
Mol.F.: C23H29N9O2
Mol.Wt.: 463.5
Inv. Status: In Stock

Ribociclib Nitroso Impurity 2

Picture of Ribociclib Nitroso Impurity 2
CAT No: SZ-R035023
CAS No: NA
Mol.F. : C23H28N10O3
Mol.Wt. : 492.5
Inv. Status: Under Synthesis
SZ-R035023
CAS No:NA
Mol.F.: C23H28N10O3
Mol.Wt.: 492.5
Inv. Status: Under Synthesis

Ribociclib Nitroso Impurity 3

Picture of Ribociclib Nitroso Impurity 3
CAT No: SZ-R035024
CAS No: NA
Mol.F. : C23H29N9O2
Mol.Wt. : 463.5
Inv. Status: Under Synthesis
SZ-R035024
CAS No:NA
Mol.F.: C23H29N9O2
Mol.Wt.: 463.5
Inv. Status: Under Synthesis