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Ribociclib Impurity 5

SZ CAT No SZ-R035012
CAS No NA
Mol.F. C21H25N7O3 . 2HCl
Mol.Wt. 423.5 . 2(36.5)
Inv. Status Out of Stock, Under Synthesis


Chemical Name: 2-((6-carboxy-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide Dihydrochloride

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.