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Ribociclib N-Desmethyl Metabolite

SZ CAT No SZ-R035004
CAS No NA
Mol.F. C22H28N8O : HCl
Mol.Wt. 420.5 : 36.5
Inv. Status In Stock
Rel. CAS No 1211441-59-6 (Free base)


Chemical Name: 7-cyclopentyl-N-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide Hydrochloride

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.