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Ribociclib Chloro Hydroxy Impurity

SZ CAT No SZ-R035007
CAS No 1374639-77-6
Mol.F. C12H14ClN3O
Mol.Wt. 251.7
Inv. Status In Stock


Chemical Name: (2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.