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Ribociclib Impurity 2

SZ CAT No SZ-R035009
CAS No NA
Mol.F. C23H30N8O2 : HCl
Mol.Wt. 450.5 : 36.5
Inv. Status In Stock
Rel. CAS No 2069953-39-3 (Free base)


Chemical Name: 2-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide hydrochloride

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.