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Ribociclib Succinate

SZ CAT No SZ-R035002
CAS No 1374639-75-4
Mol.F. C23H30N8O . C4H6O4
Mol.Wt. 434.6 : 118.1
Inv. Status Custom Synthesis
Rel. CAS No 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1211441-98-3 (free base)


Chemical Name: 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
Alexander D. James,corresponding author 1 Hilmar Schiller, 1 Cyrille Marvalin, 1 Yi Jin, 1 Hubert Borell,  Ad F. Roffel, 3 Ulrike Glaenzel,  Yan Ji, 2 and Gian Camenisch
Pharmacol Res Perspect. 2020 Jun; 8(3): e00599.