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Spironolactone Acid

SZ CAT No SZ-S017012
CAS No NA
Mol.F. C24H34O5S 
Mol.Wt. 434.6
Inv. Status Under Synthesis


Chemical Name: 3-((7R,8R,9S,10R,13S,14S,17R)-7-(Acetylthio)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanoic acid

Smiles: O=C1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@](CCC(O)=O)(O)CC[C@@]4([H])[C@]3([H])[C@H](SC(C)=O)CC2=C1

RP- HPLC method for the simultaneous estimation of losartan and spironolactone in tablet dosage form
By Chaure, Pravin P.; Sigh, Sonia; Shariff, Arshia; Wagh, Vishalkumar H.; Tandale, Sandeep D.
From Journal of Pharmaceutical Sciences and Research (2019), 11(8), 2866-2871.
 
Design of experimental approach to analytical robustness study for UHPLC method developed for separation and quantification of spironolactone and its impurities in drug substances
By Veerendra, Y. V. S.; Brahman, Pradeep Kumar; Mankumare, Sharad D.; Ch, Jaya Raju; Satish, J.
From Asian Journal of Chemistry (2020), 32(2), 219-227.
 
Influence of different chromatographic conditions on the level of detection and quantitation of spironolactone by means of TLC-densitometry
By Dolowy, Malgorzata
From Journal of Analytical Methods in Chemistry (2019), 8792783/1-8792783/8.