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Triamcinolone Acetonide EP Impurity C

SZ CAT No SZ-T026004
CAS No 161740-69-8
Mol.F. C24H31FO7 
Mol.Wt. 450.5
Inv. Status In Stock

Chemical Name: 9-fluoro-11β,21,21-trihydroxy-16α,17-(1-methylethylidenedioxy)pregna-1,4-diene-3,20-dione (as per EP) ; (9-Fluoro-11,21,21-trihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-(11β,16α)-pregna-1,4-diene-3,20-dione (as per USP)

Synonym: Triamcinolone Acetonide USP Related Compound C ; Triamcinolone Acetonide 21-Aldehydehydrate

Smiles: C[C@@]12[C@@]3(C(C(O)O)=O)[C@H](OC(O3)(C)C)C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O.C[C@@]67[C@@]8(C(C=O)=O)[C@H](OC(O8)(C)C)C[C@@]6([H])[C@]9([H])CCC%10=CC(C=C[C@]%10(C)[C@@]9(F)[C@@H](O)C7)=O

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991
Stability indicating HPTLC determination of triamcinalone acetonide in bulk drug and sterile injectable suspension
By Kulyadi, Girish Pai; Sathyanarayana, Muddukrishna Badamane
From Journal of Young Pharmacists (2016), 8(4), 430-435

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270