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21-​Methoxy Triamcinolone Acetonide

SZ CAT No SZ-T026008
CAS No 161740-70-1
Mol.F. C25H33FO7
Mol.Wt. 464.5
Inv. Status Out of Stock


Chemical Name: (6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-6b-fluoro-7-hydroxy-8b-(2-hydroxy-2-methoxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

Synonym: 21-Methoxy Triamcinolone Acetonide

Smiles: O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C5)(OC(C)(C)O1)[C@]25C)C(O)OC

Inchi: InChI=1S/C22H27N3O6/c1-28-7-9-30-20-12-17-18(13-21(20)31-10-8-29-2)23-14-24-22(17)25-16-3-4-19(27)15(11-16)5-6-26/h3-4,11-14,26-27H,5-10H2,1-2H3,(H,23,24,25)

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991
 
Stability indicating HPTLC determination of triamcinalone acetonide in bulk drug and sterile injectable suspension
By Kulyadi, Girish Pai; Sathyanarayana, Muddukrishna Badamane
From Journal of Young Pharmacists (2016), 8(4), 430-435

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270