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Triamcinolone Acetonide

SZ CAT No SZ-T026001
CAS No 76-25-5
Mol.F. C24H31FO6 
Mol.Wt. 434.5
Inv. Status In Stock


Chemical Name: 9-Fluoro-11β,21-dihydroxy-16α,17-(1-methylethylidenedioxy)pregna-1,4-diene-3,20-dione (as per EP); (9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-(11β,16α)-pregna-1,4-diene-3,20-dione (as per USP)

Synonym: Triamcinolone Hexacetonide EP Impurity A

Smiles: C[C@@]12[C@@]3(C(CO)=O)[C@H](OC(O3)(C)C)C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O

Inchi: InChI=1/C19H25NO3/c1-14(2)20-12-17(21)16-9-10-18(19(11-16)22-3)23-13-15-7-5-4-6-8-15/h4-11,14,17,20-21H,12-13H2,1-3H3

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991
 
Stability indicating HPTLC determination of triamcinalone acetonide in bulk drug and sterile injectable suspension
By Kulyadi, Girish Pai; Sathyanarayana, Muddukrishna Badamane
From Journal of Young Pharmacists (2016), 8(4), 430-435

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270