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Sorafenib IP Impurity B

SZ CAT No SZ-S012036
CAS No 2514724-45-7
Mol.F. C25H14Cl2F4N2O
Mol.Wt. 505.3
Inv. Status In Stock


Chemical Name: 1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea

Smiles: FC1=CC=CC(C2=CC(NC(NC3=CC=C(Cl)C(C4=CC=CC(F)=C4F)=C3)=O)=CC=C2Cl)=C1F

Inchi: InChI=1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H/i1D,2D,3D,4D,5D

Fragmentation pathways and differentiation of positional isomers of sorafenib and structural analogues by ESI-IT-MSn and ESI-Q-TOF-MS/MS coupled with DFT calculations
By Yu, Dandan; Liang, Xianrui
From Journal of Mass Spectrometry (2018), 53(7), 579-589.
 
Box-Behnken design based statistical modelling for optimization of U PLC-MS/MS method for analysis of sorafenib in bulk and tablets
By Wanii, Tanveer A.; Alanazi, Amer M.; Zargar, Seema; Ahmad, Ajaz; Drawish, Ibrahim A.
From Journal of Computational and Theoretical Nanoscience (2015), 12(10), 3598-3604

Determination of sorafenib in human plasma by HPLC
By Liu, Weifeng; Cao, Pengjian; Zhang, Chunfang; Xia, Dongxia; Che, Shujuan; Lou, Dan; Qiu, Xiangjun
From Zhongguo Xiandai Yingyong Yaoxue (2015), 32(2), 182-185