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Sorafenib Impurity 1

SZ CAT No SZ-S012025
CAS No 2204442-52-2
Mol.F. C27H23N5O6
Mol.Wt. 513.5
Inv. Status Custom Synthesis


Chemical Name: Methyl 4-(4-(3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)phenoxy)picolinate

Smiles: COC(C1=CC(OC2=CC=C(NC(NC3=CC=C(OC4=CC(C(NC)=O)=NC=C4)C=C3)=O)C=C2)=CC=N1)=O

Fragmentation pathways and differentiation of positional isomers of sorafenib and structural analogues by ESI-IT-MSn and ESI-Q-TOF-MS/MS coupled with DFT calculations
By Yu, Dandan; Liang, Xianrui
From Journal of Mass Spectrometry (2018), 53(7), 579-589.
 
Box-Behnken design based statistical modelling for optimization of U PLC-MS/MS method for analysis of sorafenib in bulk and tablets
By Wanii, Tanveer A.; Alanazi, Amer M.; Zargar, Seema; Ahmad, Ajaz; Drawish, Ibrahim A.
From Journal of Computational and Theoretical Nanoscience (2015), 12(10), 3598-3604

Determination of sorafenib in human plasma by HPLC
By Liu, Weifeng; Cao, Pengjian; Zhang, Chunfang; Xia, Dongxia; Che, Shujuan; Lou, Dan; Qiu, Xiangjun
From Zhongguo Xiandai Yingyong Yaoxue (2015), 32(2), 182-185