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Sorafenib Impurity 7

SZ CAT No SZ-S012045
CAS No 1012058-77-3
Mol.F. C12H10N2O3
Mol.Wt. 230.2
Inv. Status Custom Synthesis


Chemical Name: 4-(4-Aminophenoxy)picolinic acid

Smiles: OC(C1=NC=CC(OC2=CC=C(N)C=C2)=C1)=O

Inchi: InChI=1/C30H32Cl3NO.ClH/c1-3-5-13-34(14-6-4-2)29(19-35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28;/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3;1H/b25-15-;

Fragmentation pathways and differentiation of positional isomers of sorafenib and structural analogues by ESI-IT-MSn and ESI-Q-TOF-MS/MS coupled with DFT calculations
By Yu, Dandan; Liang, Xianrui
From Journal of Mass Spectrometry (2018), 53(7), 579-589.
 
Box-Behnken design based statistical modelling for optimization of U PLC-MS/MS method for analysis of sorafenib in bulk and tablets
By Wanii, Tanveer A.; Alanazi, Amer M.; Zargar, Seema; Ahmad, Ajaz; Drawish, Ibrahim A.
From Journal of Computational and Theoretical Nanoscience (2015), 12(10), 3598-3604

Determination of sorafenib in human plasma by HPLC
By Liu, Weifeng; Cao, Pengjian; Zhang, Chunfang; Xia, Dongxia; Che, Shujuan; Lou, Dan; Qiu, Xiangjun
From Zhongguo Xiandai Yingyong Yaoxue (2015), 32(2), 182-185