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Nifedipine Impurity 6

SZ CAT No SZ-N003014
Mol.F. C25H35N3O7S
Mol.Wt. 521.6
Inv. Status Custom Synthesis

Chemical Name: (1S, 2R)-Benzyl-3-[n-butyl (4-nitrobenzenesulfonyl)-amino]-2-hydroxypropyl carbamic acid tert-butyl ester

Smiles: O=C(OC(C)(C)C)N[C@@H](CC1=CC=CC=C1)[C@H](O)CN(CCCC)S(=O)(C2=CC=C([N+]([O-])=O)C=C2)=O

Inchi: InChI=1S/C24H33N3O7S/c1-5-15-26(35(32,33)20-13-11-19(12-14-20)27(30)31)17-22(28)21(16-18-9-7-6-8-10-18)25-23(29)34-24(2,3)4/h6-14,21-22,28H,5,15-17H2,1-4H3,(H,25,29)/t21-,22+/m0/s1

Rapid characterization of impurities in the bulk drug of nifedipine by high performance liquid chromatography-quadrupole time of fight mass spectrometry
Peixi Zhu 1, Lixi Ding, Jiajia He, Guogang Zheng
Se Pu. 2012 Oct;30(10):1026-30.
Development and validation of rp-hplc method for the estimation of process related impurity from nifedipine
Dr.Manisha. S. Kedar1* , Dr.Manoj. P. Shirbhate2 , Manjusha. S. Sanap3 , Dr.Rani. S. Kankate4 , Prerana. B. Jadhav5 and Bhagyashri. J. Warude
European Journal of Molecular & Clinical Medicine Volume 7, Issue 8, 2020; 5593-5601
Validation of an HPLC Method for Nifedipine and its Related Substances in Raw Materials
N. Beaulieu ,N. M. Curran,S. J. Graham,R. W. Sears &E. G. Lovering
Journal of Liquid Chromatography  Volume 14, 1991 - Issue 6 Pages 1173-1183
Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine
PatitapabanaParidaaSubash ChandraMishrabSubhashreeSahoocAjitBeheradBibhukalyan PrasadNayak
Journal of Pharmaceutical Analysis Volume 6, Issue 5, October 2016, Pages 341-344