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Nifedipine Impurity 1

SZ CAT No SZ-N003009
CAS No 53055-15-5
Mol.F. C18H20N2O6
Mol.Wt. 360.4
Inv. Status Custom Synthesis


Chemical Name: 3-Ethyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: O=C(C(C(C(C=CC=C1)=C1[N](=O)=O)C(C(OC)=O)=C(C)N2)=C2C)OCC

Inchi: InChI=1S/C34H34Cl2N4S2/c35-25-11-13-33-29(23-25)39(27-7-1-3-9-31(27)41-33)17-5-15-37-19-21-38(22-20-37)16-6-18-40-28-8-2-4-10-32(28)42-34-14-12-26(36)24-30(34)40/h1-4,7-14,23-24H,5-6,15-22H2

Rapid characterization of impurities in the bulk drug of nifedipine by high performance liquid chromatography-quadrupole time of fight mass spectrometry
Peixi Zhu 1, Lixi Ding, Jiajia He, Guogang Zheng
Se Pu. 2012 Oct;30(10):1026-30.
 
Development and validation of rp-hplc method for the estimation of process related impurity from nifedipine
Dr.Manisha. S. Kedar1* , Dr.Manoj. P. Shirbhate2 , Manjusha. S. Sanap3 , Dr.Rani. S. Kankate4 , Prerana. B. Jadhav5 and Bhagyashri. J. Warude
European Journal of Molecular & Clinical Medicine Volume 7, Issue 8, 2020; 5593-5601
 
Validation of an HPLC Method for Nifedipine and its Related Substances in Raw Materials
N. Beaulieu ,N. M. Curran,S. J. Graham,R. W. Sears &E. G. Lovering
Journal of Liquid Chromatography  Volume 14, 1991 - Issue 6 Pages 1173-1183
 
Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine
PatitapabanaParidaaSubash ChandraMishrabSubhashreeSahoocAjitBeheradBibhukalyan PrasadNayak
Journal of Pharmaceutical Analysis Volume 6, Issue 5, October 2016, Pages 341-344