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Nifedipine Impurity 3

SZ CAT No SZ-N003011
CAS No 113578-26-0
Mol.F. C20H24N2O6
Mol.Wt. 388.4
Inv. Status Custom Synthesis


Chemical Name: Methyl isobutyl 1, 4-dihydro2, 6-dimethyl-4-(3-nitrophenyl) pyridine 3, 5-dicarboxylate

Smiles: O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCC(C)C

Inchi: InChI=1/C19H22N2O6/c1-10(2)27-19(23)16-12(4)20-11(3)15(18(22)26-5)17(16)13-8-6-7-9-14(13)21(24)25/h6-10,17,20H,1-5H3

Rapid characterization of impurities in the bulk drug of nifedipine by high performance liquid chromatography-quadrupole time of fight mass spectrometry
Peixi Zhu 1, Lixi Ding, Jiajia He, Guogang Zheng
Se Pu. 2012 Oct;30(10):1026-30.
 
Development and validation of rp-hplc method for the estimation of process related impurity from nifedipine
Dr.Manisha. S. Kedar1* , Dr.Manoj. P. Shirbhate2 , Manjusha. S. Sanap3 , Dr.Rani. S. Kankate4 , Prerana. B. Jadhav5 and Bhagyashri. J. Warude
European Journal of Molecular & Clinical Medicine Volume 7, Issue 8, 2020; 5593-5601
 
Validation of an HPLC Method for Nifedipine and its Related Substances in Raw Materials
N. Beaulieu ,N. M. Curran,S. J. Graham,R. W. Sears &E. G. Lovering
Journal of Liquid Chromatography  Volume 14, 1991 - Issue 6 Pages 1173-1183
 
Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine
PatitapabanaParidaaSubash ChandraMishrabSubhashreeSahoocAjitBeheradBibhukalyan PrasadNayak
Journal of Pharmaceutical Analysis Volume 6, Issue 5, October 2016, Pages 341-344