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Nifedipine Impurity 5

SZ CAT No SZ-N003013
CAS No 1332581-15-3
Mol.F. C24H33N3O7S
Mol.Wt. 507.6
Inv. Status Custom Synthesis


Chemical Name: Tert-butyl ((2S,3R)-3-hydroxy-4-((4-nitro-N-propylphenyl)sulfonamido)-1-phenylbutan-2-yl)carbamate

Smiles: O=[S](N(CCC)C[C@@H](O)[C@@H](NC(OC(C)(C)C)=O)CC1=CC=CC=C1)(C2=CC=C([N](=O)=O)C=C2)=O

Inchi: InChI=1S/C27H36N4O9S/c1-27(2,3)40-26(33)28-22(15-19-9-5-4-6-10-19)24(32)18-29(17-20-11-7-8-12-20)41(38,39)25-14-13-21(30(34)35)16-23(25)31(36)37/h4-6,9-10,13-14,16,20,22,24,32H,7-8,11-12,15,17-18H2,1-3H3,(H,28,33)/t22-,24+/m0/s1

Rapid characterization of impurities in the bulk drug of nifedipine by high performance liquid chromatography-quadrupole time of fight mass spectrometry
Peixi Zhu 1, Lixi Ding, Jiajia He, Guogang Zheng
Se Pu. 2012 Oct;30(10):1026-30.
 
Development and validation of rp-hplc method for the estimation of process related impurity from nifedipine
Dr.Manisha. S. Kedar1* , Dr.Manoj. P. Shirbhate2 , Manjusha. S. Sanap3 , Dr.Rani. S. Kankate4 , Prerana. B. Jadhav5 and Bhagyashri. J. Warude
European Journal of Molecular & Clinical Medicine Volume 7, Issue 8, 2020; 5593-5601
 
Validation of an HPLC Method for Nifedipine and its Related Substances in Raw Materials
N. Beaulieu ,N. M. Curran,S. J. Graham,R. W. Sears &E. G. Lovering
Journal of Liquid Chromatography  Volume 14, 1991 - Issue 6 Pages 1173-1183
 
Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine
PatitapabanaParidaaSubash ChandraMishrabSubhashreeSahoocAjitBeheradBibhukalyan PrasadNayak
Journal of Pharmaceutical Analysis Volume 6, Issue 5, October 2016, Pages 341-344