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Lopinavir Impurity 4

SZ CAT No SZ-L008039
CAS No NA
Mol.F. C38H50N4O5
Mol.Wt. 642.8
Inv. Status Custom Synthesis


Chemical Name: (S)-N-((2R,4S,5S)-5-(2-(2,6-dimethylphenoxy)-N-methylacetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide

Smiles: CC(C)[C@H](N1CCCNC1=O)C(N[C@@H](C[C@H](O)[C@@H](N(C(COC2=C(C)C=CC=C2C)=O)C)CC3=CC=CC=C3)CC4=CC=CC=C4)=O

Inchi: InChI=1S/C38H50N4O5/c1-26(2)35(42-21-13-20-39-38(42)46)37(45)40-31(22-29-16-8-6-9-17-29)24-33(43)32(23-30-18-10-7-11-19-30)41(5)34(44)25-47-36-27(3)14-12-15-28(36)4/h6-12,14-19,26,31-33,35,43H,13,20-25H2,1-5H3,(H,39,46)(H,40,45)/t31-,32+,33-,35+/m1/s1

Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
By Srinivas, L.; Jain, Neelu
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792
 
Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas
From International Research Journal of Pharmacy (2018), 9(8), 57-62
 
Development and validation of forced degradation studies of lopinavir using RP-​HPLC and characterization of degradants by LC-​MS​/MS
By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M.
From International Journal of Chemical Sciences (2015), 13(1), 551-562