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Lopinavir EP Impurity A

SZ CAT No SZ-L008002
CAS No 192726-05-9
Mol.F. C27H38N4O3
Mol.Wt. 466.6
Inv. Status In Stock


Chemical Name: (2S)-N-[(1S,3S,4S)-1-Benzyl-4-amino-3-hydroxy-5-phenylpentyl]-3-methyl-2-[2-oxotetrahydropyrimidin1(2H)-yl]butanamide (as per EP); (S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide (as per USP)

Synonym: Lopinavir Free Amine (USP)

Smiles: CC(C)[C@H](N1CCCNC1=O)C(N[C@@H](CC2=CC=CC=C2)C[C@H](O)[C@@H](N)CC3=CC=CC=C3)=O

Inchi: InChI=1S/C28H38N4O4/c1-20(2)26(32-15-9-14-29-28(32)36)27(35)31-23(16-21-10-5-3-6-11-21)18-25(34)24(30-19-33)17-22-12-7-4-8-13-22/h3-8,10-13,19-20,23-26,34H,9,14-18H2,1-2H3,(H,29,36)(H,30,33)(H,31,35)/t23-,24-,25-,26-/m0/s1

Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
By Srinivas, L.; Jain, Neelu
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792
 
Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
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From International Research Journal of Pharmacy (2018), 9(8), 57-62
 
Development and validation of forced degradation studies of lopinavir using RP-​HPLC and characterization of degradants by LC-​MS​/MS
By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M.
From International Journal of Chemical Sciences (2015), 13(1), 551-562