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Lopinavir Impurity 1

SZ CAT No SZ-L008029
CAS No NA
Mol.F. C37H46N4O5
Mol.Wt. 626.8
Inv. Status Under Synthesis


Chemical Name: (S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxo-3,6-dihydropyrimidin-1(2H)-yl)butanamide

Smiles: O=C([C@H](C(C)C)N1CC=CNC1=O)N[C@@H](CC2=CC=CC=C2)C[C@H](O)[C@@H](NC(COC3=C(C)C=CC=C3C)=O)CC4=CC=CC=C4

Inchi: InChI=1S/C45H42Cl2N8O8/c1-4-41(54-42(56)29-19-27-35(21-39(29)60-2)48-15-13-37(27)62-25-9-11-33(31(46)17-25)52-44(58)50-23-5-6-23)55-43(57)30-20-28-36(22-40(30)61-3)49-16-14-38(28)63-26-10-12-34(32(47)18-26)53-45(59)51-24-7-8-24/h9-24,41H,4-8H2,1-3H3,(H,54,56)(H,55,57)(H2,50,52,58)(H2,51,53,59)

Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
By Srinivas, L.; Jain, Neelu
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792
 
Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas
From International Research Journal of Pharmacy (2018), 9(8), 57-62
 
Development and validation of forced degradation studies of lopinavir using RP-​HPLC and characterization of degradants by LC-​MS​/MS
By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M.
From International Journal of Chemical Sciences (2015), 13(1), 551-562