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Lopinavir EP Impurity M 

SZ CAT No SZ-L008014
CAS No NA
Mol.F. C37H48N4O5 
Mol.Wt. 628.8
Inv. Status In Stock


Chemical Name: (2S)-N-[(1R,3R,4S)-1-Benzyl-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenylpentyl]3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide (as per EP); (S)-N-{(2R,4R,5S)-5-[2-(2,6-Dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl}-3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide (as per USP)

Synonym: Lopinavir (2R, 4R)-Diastereomer (USP)

Smiles: CC(C)[C@H](N1CCCNC1=O)C(N[C@H](CC2=CC=CC=C2)C[C@@H](O)[C@@H](NC(COC3=C(C)C=CC=C3C)=O)CC4=CC=CC=C4)=O

Inchi: InChI=1S/C22H26N2O4/c1-15-7-5-8-16(2)21(15)27-13-19(25)23-11-12-24-20(26)14-28-22-17(3)9-6-10-18(22)4/h5-12H,13-14H2,1-4H3,(H,23,25)(H,24,26)/b12-11-

Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
By Srinivas, L.; Jain, Neelu
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792
 
Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas
From International Research Journal of Pharmacy (2018), 9(8), 57-62
 
Development and validation of forced degradation studies of lopinavir using RP-​HPLC and characterization of degradants by LC-​MS​/MS
By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M.
From International Journal of Chemical Sciences (2015), 13(1), 551-562