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Lansoprazole Hydroxymethyl Impurity

SZ CAT No SZ-L009009
CAS No 103577-66-8
Mol.F. C9H10F3NO2
Mol.Wt.  221.2
Inv. Status Custom Synthesis


Chemical Name:  2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine

Smiles: FC(F)(F)COC1=C(C)C(CO)=NC=C1

Inchi: InChI=1S/C14H12ClN3S/c1-9-10(15)6-7-16-13(9)8-19-14-17-11-4-2-3-5-12(11)18-14/h2-7H,8H2,1H3,(H,17,18)

Analytical Quality by Design (AQbD)-oriented RPUFLC method for quantification of lansoprazole with superior method robustness
Sagar Suman Panda, Venkata Varaha Ravi Kumar Bera, Sarwar Beg & Omkar Mandal
Journal of Liquid Chromatography & Related Technologies  Volume 40, 2017 - Issue 9 Pages 479-485
 
Identification, isolation and characterization of potential degradation product in lansoprazole drug substance
K.Ramulu1 , B.M. Rao2* and N.Someswara Rao
Rasayan J. Chem. Vol. 6 | No.4 | 274 - 283 | October- December| 2013
 
Development and validation of an enantioselective and chemoselective HPLC method using a Chiralpak IA column to simultaneously quantify (R)-(+)- and (S)-(−)-lansoprazole enantiomers and related impurities
Roberto Cirilli, Rosella Ferretti ∗, Bruno Gallinella, Luciana Turchetto, Leo Zanitti, Francesco La Torre
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 9–14