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Lansoprazole EP Impurity A

SZ CAT No SZ-L009002
CAS No 213476-12-1
Mol.F. C16H14F3N3O3S
Mol.Wt. 385.4
Inv. Status In Stock


Chemical Name: 2-[(RS)-[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole (as per EP)

Synonym:  Lansoprazole N-Oxide

Smiles: O=S(C1=NC2=CC=CC=C2N1)CC3=C(C)C(OCC(F)(F)F)=CC=[N+]3[O-]

Inchi: InChI=1/C16H13F3N3O2S.Na/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15;/h2-7H,8-9H2,1H3;/q-1;+1

Analytical Quality by Design (AQbD)-oriented RPUFLC method for quantification of lansoprazole with superior method robustness
Sagar Suman Panda, Venkata Varaha Ravi Kumar Bera, Sarwar Beg & Omkar Mandal
Journal of Liquid Chromatography & Related Technologies  Volume 40, 2017 - Issue 9 Pages 479-485
 
Identification, isolation and characterization of potential degradation product in lansoprazole drug substance
K.Ramulu1 , B.M. Rao2* and N.Someswara Rao
Rasayan J. Chem. Vol. 6 | No.4 | 274 - 283 | October- December| 2013
 
Development and validation of an enantioselective and chemoselective HPLC method using a Chiralpak IA column to simultaneously quantify (R)-(+)- and (S)-(−)-lansoprazole enantiomers and related impurities
Roberto Cirilli, Rosella Ferretti ∗, Bruno Gallinella, Luciana Turchetto, Leo Zanitti, Francesco La Torre
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 9–14