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Clozapine Nitroso EP Impurity C

SZ CAT No SZ-C008018
CAS No NA
Mol.F. C17H16ClN5O
Mol.Wt. 341.8
Inv. Status Custom Synthesis


Chemical Name: 8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Smiles: O=NN(CC1)CCN1C2=NC3=C(NC4=C2C=CC=C4)C=CC(Cl)=C3

Inchi: InChI=1/C11H21NO.ClH/c1-3-4-10(2)9-12-7-5-11(13)6-8-12;/h10H,3-9H2,1-2H3;1H

Validated LC–MS-MS Method for the Determination of Quetiapine in Human Plasma: Application to a Pharmacokinetic Study
Ryh-Nan Pan, Benjamin Pei-Chung Kuo, Li-Heng Pao
Journal of Chromatographic Science, Volume 50, Issue 3, March 2012, Pages 277–282
 
Characterization of forced degradation products of clozapine by LC-DAD/ESI-Q-TOF.
Skibiński , Trawiński , Komsta , Bajda
Journal of Pharmaceutical and Biomedical Analysis, 04 Sep 2016, 131:272-280