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Clozapine EP Impurity C

SZ CAT No SZ-C008004
CAS No 6104-71-8
Mol.F. C17H17ClN4
Mol.Wt.  312.8
Inv. Status In Stock


Chemical Name: 8-Chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Synonym: Clozapine impurity A (USP)

Smiles: ClC1=CC=C2C(N=C(N3CCNCC3)C4=CC=CC=C4N2)=C1

Inchi: InChI=1S/C30H24Cl2N6/c31-19-9-11-25-27(17-19)35-29(21-5-1-3-7-23(21)33-25)37-13-15-38(16-14-37)30-22-6-2-4-8-24(22)34-26-12-10-20(32)18-28(26)36-30/h1-12,17-18,33-34H,13-16H2

Validated LC–MS-MS Method for the Determination of Quetiapine in Human Plasma: Application to a Pharmacokinetic Study
Ryh-Nan Pan, Benjamin Pei-Chung Kuo, Li-Heng Pao
Journal of Chromatographic Science, Volume 50, Issue 3, March 2012, Pages 277–282
 
Characterization of forced degradation products of clozapine by LC-DAD/ESI-Q-TOF.
Skibiński , Trawiński , Komsta , Bajda
Journal of Pharmaceutical and Biomedical Analysis, 04 Sep 2016, 131:272-280