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Clozapine EP Impurity B

SZ CAT No SZ-C008003
CAS No 263366-81-0
Mol.F. C30H24Cl2N6
Mol.Wt. 539.5
Inv. Status In Stock


Chemical Name: 1,4-Bis(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazine

Synonym: Clozapine impurity D (USP)

Smiles: ClC1=CC=C2C(N=C(N3CCN(C4=NC5=CC(Cl)=CC=C5NC6=CC=CC=C46)CC3)C7=CC=CC=C7N2)=C1

Inchi: InChI=1S/C13H9ClN2O/c14-8-5-6-11-12(7-8)16-13(17)9-3-1-2-4-10(9)15-11/h1-7,15H,(H,16,17)

Validated LC–MS-MS Method for the Determination of Quetiapine in Human Plasma: Application to a Pharmacokinetic Study
Ryh-Nan Pan, Benjamin Pei-Chung Kuo, Li-Heng Pao
Journal of Chromatographic Science, Volume 50, Issue 3, March 2012, Pages 277–282
 
Characterization of forced degradation products of clozapine by LC-DAD/ESI-Q-TOF.
Skibiński , Trawiński , Komsta , Bajda
Journal of Pharmaceutical and Biomedical Analysis, 04 Sep 2016, 131:272-280