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Alvespimycin is a compound derived from geldanamycin and acts as an inhibitor of heat shock protein (HSP) 90. It has been investigated in clinical trials for its potential to treat solid tumors in various types of cancer as an antitumor agent. Compared to the first HSP90 inhibitor, tanespimycin, alvespimycin offers several beneficial pharmacological properties, including lower metabolic risk, reduced plasma protein binding, improved water solubility, enhanced oral bioavailability, decreased liver toxicity, and more effective antitumor activity.


SynZeal 是药用对照品领域的领先创新者。我们提供高质量的对照品 Alvespimycin,药典及非药典 Alvespimycin 杂质、代谢物、稳定同位素产品以及亚硝胺(N-NO 产品)。 Alvespimycin 杂质对照品在药物研发中非常有用。它们在产品开发、ANDA 和 DMF 申报、质量控制(QC)、方法验证及稳定性研究中均有应用。同时,它们也用于未知杂质的识别及基因毒性潜力的评估。

Alvespimycin-相关产品经过全面表征。 Alvespimycin 产品提供详细的 COA 和分析数据,以满足法规合规要求。我们还可以根据您的需求提供可追溯到 EP/USP 的标准。所提供的产品会定期进行复检。