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Spironolactone Impurity 1

N° de SZ CAT SZ-S017013
Número CAS 38753-75-2
Mol.F. C23H30O4S 
Peso Molecular 402.6
Status de Fatura Custom Synthesis


Nome Químico: (7R,8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-7-((S)-methylsulfinyl)-1,3',4',6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

Sorrisos: C[C@@]12[C@@]3([H])CC[C@@]([C@@]4(OC(CC4)=O)CC5)(C)[C@]5([H])[C@]3([H])[C@H]([S@](C)=O)CC1=CC(CC2)=O

Inchi: InChI=1S/C24H34O5S/c1-14(25)30-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23,29)11-7-20(27)28/h12,17-19,21,29H,4-11,13H2,1-3H3,(H,27,28)/t17-,18-,19+,21+,22-,23-,24+/m0/s1

RP- HPLC method for the simultaneous estimation of losartan and spironolactone in tablet dosage form
By Chaure, Pravin P.; Sigh, Sonia; Shariff, Arshia; Wagh, Vishalkumar H.; Tandale, Sandeep D.
From Journal of Pharmaceutical Sciences and Research (2019), 11(8), 2866-2871.
 
Design of experimental approach to analytical robustness study for UHPLC method developed for separation and quantification of spironolactone and its impurities in drug substances
By Veerendra, Y. V. S.; Brahman, Pradeep Kumar; Mankumare, Sharad D.; Ch, Jaya Raju; Satish, J.
From Asian Journal of Chemistry (2020), 32(2), 219-227.
 
Influence of different chromatographic conditions on the level of detection and quantitation of spironolactone by means of TLC-densitometry
By Dolowy, Malgorzata
From Journal of Analytical Methods in Chemistry (2019), 8792783/1-8792783/8.