Nome Químico: S-[(2′R)-3,5′-Dioxo-5′H-spiro[androst-4-ene-17,2′-furan]-7α-yl] ethanethioate (as per EP); (2′R)-7α-(Acetylthio)-5′H-spiro[androst-4-ene-17,2′-furan]-3,5′-dione (as per USP)
Sinônimo: Spironolactone USP Related Compound B ; Δ20-Spironolactone
Sorrisos: C[C@@]12[C@]3(C=CC(O3)=O)CC[C@@]1([H])[C@]4([H])[C@H](SC(C)=O)CC5=CC(CC[C@]5(C)[C@@]4([H])CC2)=O
Inchi: InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
RP- HPLC method for the simultaneous estimation of losartan and spironolactone in tablet dosage form
By Chaure, Pravin P.; Sigh, Sonia; Shariff, Arshia; Wagh, Vishalkumar H.; Tandale, Sandeep D.
From Journal of Pharmaceutical Sciences and Research (2019), 11(8), 2866-2871.
Design of experimental approach to analytical robustness study for UHPLC method developed for separation and quantification of spironolactone and its impurities in drug substances
By Veerendra, Y. V. S.; Brahman, Pradeep Kumar; Mankumare, Sharad D.; Ch, Jaya Raju; Satish, J.
From Asian Journal of Chemistry (2020), 32(2), 219-227.
Influence of different chromatographic conditions on the level of detection and quantitation of spironolactone by means of TLC-densitometry
By Dolowy, Malgorzata
From Journal of Analytical Methods in Chemistry (2019), 8792783/1-8792783/8.
