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Spironolactone EP Impurity E

N° de SZ CAT SZ-S017006
Número CAS 33784-05-3
Mol.F. C24H32O4S
Peso Molecular 416.5
Status de Fatura In Stock


Nome Químico: S-[(2′R)-3,5′-Dioxo-3′,4′-dihydro-5′H-spiro[androst-4-ene-17,2′-furan]-7β-yl] ethanethioate (as per EP)

Sinônimo: 7β-Spironolactone

Sorrisos: C[C@@]12[C@]3(CCC(O3)=O)CC[C@@]1([H])[C@]4([H])[C@@H](SC(C)=O)CC5=CC(CC[C@]5(C)[C@@]4([H])CC2)=O

Inchi: InChI=1/C17H15Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12H,7,9H2,1H3/b20-17+

RP- HPLC method for the simultaneous estimation of losartan and spironolactone in tablet dosage form
By Chaure, Pravin P.; Sigh, Sonia; Shariff, Arshia; Wagh, Vishalkumar H.; Tandale, Sandeep D.
From Journal of Pharmaceutical Sciences and Research (2019), 11(8), 2866-2871.
 
Design of experimental approach to analytical robustness study for UHPLC method developed for separation and quantification of spironolactone and its impurities in drug substances
By Veerendra, Y. V. S.; Brahman, Pradeep Kumar; Mankumare, Sharad D.; Ch, Jaya Raju; Satish, J.
From Asian Journal of Chemistry (2020), 32(2), 219-227.
 
Influence of different chromatographic conditions on the level of detection and quantitation of spironolactone by means of TLC-densitometry
By Dolowy, Malgorzata
From Journal of Analytical Methods in Chemistry (2019), 8792783/1-8792783/8.