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Triamcinolone EP Impurity C

SZ CAT No SZ-T028004
CAS No 337-02-0
Mol.F. C21H29FO6
Mol.Wt. 396.5
Inv. Status In Stock


Chemical Name: 9-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione (as per EP)

Synonym: Pretriamcinolone ; 1,2-Dihydro Triamcinolone

Smiles: F[C@@]1([C@]2(CC3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@](O)([H])[C@]4(O)C(CO)=O)([H])[C@]4(C)C[C@]1([H])O

Inchi: InChI=1S/C9H9NO4/c1-5(11)10-7-3-2-6(9(13)14)4-8(7)12/h2-4,12H,1H3,(H,10,11)(H,13,14)

Δ14-​steroidal impurity: preparation, characterization and evaluation, as well development of new HPLC method in drug substance like Triamcinolone Hexacetonide
By Shah, Tejas J.; Thakore, Anant R.; Chheda, Abhay H.; Desai, Geeta R.; Tandel, Harish S.
From Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry (2020), 8(1), 7-15
 
Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270