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Sofosbuvir Impurity 76

SZ CAT No SZ-S010099
CAS No NA
Mol.F. C24H21ClFN3O5
Mol.Wt. 485.9
Inv. Status Out of Stock


Chemical Name: (2S,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-(chloromethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

Synonym: Sofosbuvir-12-5'-Chloro Impurity

Smiles: C[C@@]1(F)[C@H](OC(C2=CC=CC=C2)=O)[C@@H](CCl)O[C@H]1N3C(N=C(NC(C4=CC=CC=C4)=O)C=C3)=O

Inchi: InChI=1S/C18H17F5NO5P/c1-9(2)27-18(25)10(3)24-30(26,28-11-7-5-4-6-8-11)29-17-15(22)13(20)12(19)14(21)16(17)23/h4-10H,1-3H3,(H,24,26)/t10-,30-/m0/s1

Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.
 
Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.
 
Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.