Chemical Name: Isopropyl ((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
Smiles: F[C@]1(C)[C@H](O[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)[C@@H](CO)O[C@@H]1N3C(NC(C=C3)=O)=O
Inchi: InChI=1S/C35H47FN4O12P2/c1-22(2)48-31(42)24(5)38-53(45,21-26-14-10-8-11-15-26)47-20-28-30(35(7,36)33(50-28)40-19-18-29(41)37-34(40)44)52-54(46,51-27-16-12-9-13-17-27)39-25(6)32(43)49-23(3)4/h8-19,22-25,28,30,33H,20-21H2,1-7H3,(H,38,45)(H,39,46)(H,37,41,44)/t24-,25-,28+,30+,33-,35+,53+,54+/m0/s1
Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.
Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.
Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.