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Sofosbuvir Impurity 58

SZ CAT No SZ-S010081
CAS No 1015073-43-4
Mol.F. C10H14FN2O8P
Mol.Wt. 340.2
Inv. Status Custom Synthesis


Chemical Name: ((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen phosphate

Smiles: F[C@]1(C)[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C(NC(C=C2)=O)=O

Inchi: InChI=1S/C10H15FN2O11P2/c1-10(11)7(24-26(19,20)21)5(4-22-25(16,17)18)23-8(10)13-3-2-6(14)12-9(13)15/h2-3,5,7-8H,4H2,1H3,(H,12,14,15)(H2,16,17,18)(H2,19,20,21)/t5-,7-,8-,10-/m1/s1

Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.
 
Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.
 
Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.