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Sofosbuvir Impurity 52

SZ CAT No SZ-S010075
CAS No 2073854-58-5
Mol.F. C23H18N2O8
Mol.Wt. 450.4
Inv. Status Custom Synthesis


Chemical Name: ((2R,3R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-oxotetrahydrofuran-2-yl)methyl benzoate

Smiles: O=C(NC(C=C1)=O)N1[C@H](O[C@H](COC(C2=CC=CC=C2)=O)[C@H]3OC(C4=CC=CC=C4)=O)C3=O

Inchi: InChI=1S/C24H20N2O7/c1-15-20(33-23(29)17-10-6-3-7-11-17)18(14-31-22(28)16-8-4-2-5-9-16)32-21(15)26-13-12-19(27)25-24(26)30/h2-13,18,20-21H,1,14H2,(H,25,27,30)/t18-,20+,21-/m1/s1

Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.
 
Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.
 
Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.