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Sofosbuvir Impurity 20

SZ CAT No SZ-S010043
CAS No NA
Mol.F. C24H22FN3O6
Mol.Wt. 467.5
Inv. Status Custom Synthesis


Chemical Name: (2R,3R,4S,5S)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

Smiles: C[C@]1(F)[C@H](OC(C2=CC=CC=C2)=O)[C@@H](COC(C3=CC=CC=C3)=O)O[C@@H]1N4C(N=C(N)C=C4)=O

Inchi: InChI=1S/C24H22FN3O6/c1-24(25)19(34-21(30)16-10-6-3-7-11-16)17(14-32-20(29)15-8-4-2-5-9-15)33-22(24)28-13-12-18(26)27-23(28)31/h2-13,17,19,22H,14H2,1H3,(H2,26,27,31)/t17-,19-,22-,24+/m1/s1

Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.
 
Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.
 
Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.