Chemical Name: (1RS,4RS)-4-(3-chlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (as per EP)
Synonym: Sertraline 3-Chlorophenyl Analog ; 4-Deschloro Sertraline
Smiles: CN[C@H]1CC[C@@H](C2=CC=CC(Cl)=C2)C3=C1C=CC=C3.Cl
Inchi: InChI=1S/C17H18ClN.ClH/c1-19-17-11-10-14(12-6-8-13(18)9-7-12)15-4-2-3-5-16(15)17;/h2-9,14,17,19H,10-11H2,1H3;1H/t14-,17-;/m0./s1
Separation of stereoisomers of sertraline and its related enantiomeric impurities on a dimethylated β-cyclodextrin stationary phase by HPLC
R. Nageswara Rao M.V.N. KumarTalluri Pawan K.Maurya
Journal of Pharmaceutical and Biomedical Analysis Volume 50, Issue 3, 15 October 2009, Pages 281-286
Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities
Alessia Ferrarini , Angel Luis Huidobro, Federica Pellati, Coral Barbas
J Pharm Biomed Anal. 2010 Oct 10;53(2):122-9
UHPLC Determination of Enantiomeric Purity of Sertraline in the Presence of its Production Impurities
M. L. Reyes-Reyes, Gabriela Roa-Morales, Roberto Melgar-Fernández, Horacio Reyes-Pérez & Patricia Balderas-Hernández
Chromatographia volume 77, pages1315–1321(2014)