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Prednisolone Epoxide-Triene Impurity

SZ CAT No SZ-P027050
CAS No NA
Mol.F. C21H24O4
Mol.Wt. 340.4
Inv. Status Custom Synthesis


Chemical Name: (4aS,4bS,5aS,6aS)-7-(2-hydroxyacetyl)-4a,6a-dimethyl-5a,6,6a,9,9a,9b,10,11-octahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one ; 9 β,11 β -epoxide-21-hydroxy pregna-1,4,16-triene-3,20-dione

Smiles: O=C1C=C[C@@]([C@]2(O3)[C@@H]3C[C@@](C(C(CO)=O)=CC4)(C)C4C2CC5)(C)C5=C1

Inchi: InChI=1S/C10H9ClN2/c1-7-8-4-2-3-5-9(8)13-10(6-11)12-7/h2-5H,6H2,1H3

Validated stability indicating RP-​LC assay for determination of gatifloxacin and prednisolone acetatein ophthalmic preparations and biological samples
By Qadir, Muhammad A.; Shahzad, Shabnam; Ahmed, Mahmood; Razzaq, Syed S.; Shafiq, Muhmmad I.
From Latin American Journal of Pharmacy (2016), 35(5), 912-920
 
Novel stability indicating RP-​HPLC method for the simultaneous estimation of moxifloxacin and prednisolone in bulk and their combined dosage form
By Potnuri, Naga Raju; Rao, G. Devala; Prasad, Y. Rajendra
From International Journal of Pharmaceutical Sciences and Research (2015), 6(5), 1965-1973
 
Development and validation of a new stability indicating reversed phase liquid chromatographic method for the determination of prednisolone acetate and impurities in an ophthalmic suspension
By Marley, Adrian; Stalcup, Apryll M.; Connolly, Damian
From Journal of Pharmaceutical and Biomedical Analysis (2015), 102, 261-266