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Posaconazole Impurity 74

SZ CAT No SZ-P022108
CAS No 2199938-47-9
Mol.F. C21H21F2N3O4S
Mol.Wt. 449.5
Inv. Status Custom Synthesis

Chemical Name: ((2R,3S,5R)-5-(2,4-difluorophenyl)-2-methyl-5-(1H-1,2,4-triazol-1-yl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

Smiles: FC1=C([C@@]2(N3C=NC=N3)C[C@@H](CO[S](=O)(C4=CC=C(C)C=C4)=O)[C@@H](C)O2)C=CC(F)=C1

Inchi: InChI=1S/C16H19N3O/c17-13-1-3-14(4-2-13)18-9-11-19(12-10-18)15-5-7-16(20)8-6-15/h1-8,20H,9-12,17H2

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..