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Posaconazole 1,2,4-Triazole impurity

SZ CAT No SZ-P022081
Mol.F. C15H21N3O
Mol.Wt. 259.4
Inv. Status Custom Synthesis

Chemical Name: 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-5-methyl-1H-1,2,4-Triazole

Smiles: CC1=NC=NN1[C@@H](CC)[C@@H](OCC2=CC=CC=C2)C

Inchi: InChI=1S/C36H40N2.H/c1-36(2,3)24-12-14-29(26-38(5)28-33-21-11-19-31-17-7-9-23-35(31)33)15-13-25-37(4)27-32-20-10-18-30-16-6-8-22-34(30)32;/h6-11,13-23H,25-28H2,1-5H3;/b15-13+,29-14+;/i;1+1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..