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Piperacillin EP Impurity T

SZ CAT No SZ-P048008
CAS No 2170771-53-4
Mol.F. C46H54N10O14S2
Mol.Wt. 1035.1
Inv. Status In Stock

Chemical Name: (2Ξ,4S)-2-[(Ξ)-carboxy[(2R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]methyl]-3-[(2S,5R,6R)-6-[(2R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbonyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (as per EP)

Synonym: Piperacillin dimer

Smiles: O=C([C@@H]1N(C([C@@H](C(C)(C)S[C@]2([H])[C@@H]3NC([C@H](NC(N4C(C(N(CC)CC4)=O)=O)=O)C5=CC=CC=C5)=O)N2C3=O)=O)[C@@H]([C@@H](C(O)=O)NC([C@H](NC(N6C(C(N(CC)CC6)=O)=O)=O)C7=CC=CC=C7)=O)SC1(C)C)O

Inchi: InChI=1S/C25H31N5O9S/c1-5-28-11-12-29(20(34)19(28)33)24(39)27-15(14-9-7-6-8-10-14)18(32)26-16(22(35)36)21-30(13(2)31)17(23(37)38)25(3,4)40-21/h6-10,15-17,21H,5,11-12H2,1-4H3,(H,26,32)(H,27,39)(H,35,36)(H,37,38)/t15-,16?,17+,21?/m1/s1

Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-​tandem mass spectrometry method, part 2: stability evaluation
By D'cunha, Ronilda; Bach, Thanh; Young, Beth Ann; Li, Peizhi; Nalbant, Demet; Zhang, Jun; Winokur, Patricia; An, Guohua
From Antimicrobial Agents and Chemotherapy (2018), 62(9), e00861-18/1-e00861-18/9
Stability indicating RP-​HPLC method for the determination of Piperacillin and Tazobactam and their related substances in bulk and pharmaceutical formulation
By Navle, Khyathi; Prasanna, B. Lakshmi; Dometti, Hema Sree; Moodu, Shankar
From World Journal of Pharmacy and Pharmaceutical Sciences (2017), 6(8), 1760-1774

Therapeutic drug monitoring of beta-​lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-​UV
By Pinder, Nadine; Brenner, Thorsten; Swoboda, Stefanie; Weigand, Markus A.; Hoppe-Tichy, Torsten
From Journal of Pharmaceutical and Biomedical Analysis (2017), 143, 86-93