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Piperacillin EP Impurity B (2Na salt)

SZ CAT No SZ-P048026
CAS No NA
Mol.F. C23H29N5O8S : 2Na
Mol.Wt. 535.6 : 2(23.0)
Inv. Status Out of Stock
Rel. CAS No 64817-22-7 (free base)


Chemical Name: (2Ξ,4S)-2-[(Ξ)-carboxy[(2R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid,disodium salt (as per EP); (2R,4S)-2-{(1R)-Carboxy[2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]methyl}-5,5-dimethylthiazolidine-4-carboxylic acid, disodium salt (as per USP)

Smiles: O=C([C@@H]1NC(C(C(O)=O)NC([C@H](NC(N2C(C(N(CC)CC2)=O)=O)=O)C3=CC=CC=C3)=O)SC1(C)C)O.[2Na]

Inchi: InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m1/s1

Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-​tandem mass spectrometry method, part 2: stability evaluation
By D'cunha, Ronilda; Bach, Thanh; Young, Beth Ann; Li, Peizhi; Nalbant, Demet; Zhang, Jun; Winokur, Patricia; An, Guohua
From Antimicrobial Agents and Chemotherapy (2018), 62(9), e00861-18/1-e00861-18/9
 
Stability indicating RP-​HPLC method for the determination of Piperacillin and Tazobactam and their related substances in bulk and pharmaceutical formulation
By Navle, Khyathi; Prasanna, B. Lakshmi; Dometti, Hema Sree; Moodu, Shankar
From World Journal of Pharmacy and Pharmaceutical Sciences (2017), 6(8), 1760-1774

Therapeutic drug monitoring of beta-​lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-​UV
By Pinder, Nadine; Brenner, Thorsten; Swoboda, Stefanie; Weigand, Markus A.; Hoppe-Tichy, Torsten
From Journal of Pharmaceutical and Biomedical Analysis (2017), 143, 86-93