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Pemetrexed EP Impurity D

SZ CAT No SZ-P014005
CAS No 144051-68-3
Mol.F. C25H28N6O9
Mol.Wt. 556.5
Inv. Status Limited Stock
Rel. CAS No 1265908-59-5 (Trisodium salt)


Chemical Name: (2S)-2-[(4S)-4-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]-4-carboxybutanamido]pentanedioic acid (as per EP); {4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-4-l-glutamyl-l-glutamic acid (as per USP)

Synonym: Pemetrexed USP impurity b

Development of a purity control strategy for pemetrexed disodium and validation of associated analytical methodology
Anne Warner ∗, Irina Piraner, Heather Weimer, Kevin White
Journal of Pharmaceutical and Biomedical Analysis 105 (2015) 46–54
 
RP-HPLC Method Validation for Quantitative Analysis of Pemetrexed Disodium Hemipentahydrate
Vitthal M. Dhalape, Santosh T. Khadangale, Rahul V. Pinjari
Research Journal of Pharmacy and Technology 2020; 13(8):3685-3689.