Chemical Name: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, monomethyl ester (9CI); (±)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid monomethyl ester; (±)-1,4-Dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester; 2,6-Dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid;
Smiles: O=C(C(C(C1=CC([N](=O)=O)=CC=C1)C(C(O)=O)=C(C)N2)=C2C)OC
Inchi: InChI=1/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181