Chemical Name: 3-(2-(Benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-nitroso-1,4-dihydropyridine-3,5-dicarboxylate
Smiles: O=C(C1=C(C)N(N=O)C(C)=C(C(OCCN(CC2=CC=CC=C2)C)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OC
Inchi: InChI=1S/C14H21N7O6/c1-7(2)9(15)13(24)26-4-8(3-22)27-6-20-5-17-10-11(23)18-14(16)21(19-25)12(10)20/h5,7-9,22H,3-4,6,15H2,1-2H3,(H2,16,18,23)/t8?,9-/m0/s1
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181