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Melphalan EP Impurity C Hydrochloride

SZ CAT No SZ-M003004
CAS No 2286317-87-9
Mol.F. C11H15ClN2O2 : HCl
Mol.Wt. 242.7 : 36.5
Inv. Status In Stock
Rel. CAS No 573704-41-3 (free base)


Chemical Name: 4-[(2-chloroethyl)amino]-L-phenylalanine Hydrochloride (as per EP)

Synonym: Melphalan Mono-chloroethyl Impurity

Encapsulation of Chemotherapeutic Drug Melphalan in Cucurbit[7]uril: Effects on Its Alkylating Activity, Hydrolysis, and Cytotoxicity
Gustavo Villarroel-Lecourt, Javiera Carrasco-Carvajal, Felipe Andrade-Villalobos, Fresia Solís-Egaña, Ignacio Merino-San Martín, José Robinson-Duggon, and Denis Fuentealba
ACS Omega 2018, 3, 7, 8337–8343
 
Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection
Ramsharan Singh, Jin Chen, Teresa Miller, Michael Bergren & Rangan Mallik
Pharmaceutical Development and Technology 23(10):1-6