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Loteprednol Impurity 6

SZ CAT No SZ-L034012
CAS No NA
Mol.F. C47H64O14
Mol.Wt. 853.0
Inv. Status Under Synthesis


Chemical Name: Methylene (8S,8'S,10R,10'R,13S,13'S,14S,14'S)-bis(17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylate)

Smiles: O=C(OCC)OC([C@]12C)(CC[C@@]1([H])[C@@](CCC3=CC4=O)([H])C([C@]3(CC4)C)C(O)C2)C(OCOC(C5(OC(OCC)=O)[C@](CC(O)C([C@@]6(C)CC7)[C@@]8([H])CCC6=CC7=O)(C)[C@@]8([H])CC5)=O)=O

Potential Use of Cyclodextrin Complexes for Enhanced Stability, Anti-​inflammatory Efficacy, and Ocular Bioavailability of Loteprednol Etabonate
By Soliman, Osama Abd El-Aazeem; Mohamed, Elham Abdel Monem; El-Dahan, Marwa Salah; Khatera, Nabil Abdullah Ali
From AAPS PharmSciTech (2017), 18(4), 1228-1241
 
Determination of edetate disodium dihydrate in loteprednol and tobramycin ophthalmic suspension by RP-​HPLC
By Xue, Qi; Yang, Longhua
From Zhongguo Yaoye (2012), 21(1), 24-25

An HPLC method to evaluate purity of a steroidal drug, loteprednol etabonate
By Yasueda, Shin-ichi; Higashiyama, Masayo; Shirasaki, Yoshihisa; Inada, Katsuhiro; Ohtori, Akira
From Journal of Pharmaceutical and Biomedical Analysis (2004), 36(2), 309-316