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Loratadine 2-Hydroxymethyl Impurity (USP)

SZ CAT No SZ-L002013
CAS No 609806-39-5
Mol.F. C23H25ClN2O3
Mol.Wt. 412.9
Inv. Status In Stock


Chemical Name: Ethyl 4-[8-chloro-5,6-dihydro-2-(hydroxy methyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidine carboxylate ;

Synonym: 2-Hydroxymethyl Loratadine (USP)

Smiles: O=C(N1CC/C(CC1)=C2C3=CC=C(Cl)C=C3CCC4=CC=C(CO)N=C4\2)OCC

Inchi: InChI=1S/C22H22Cl2N2O2/c1-2-28-22(27)26-11-9-14(10-12-26)20-18-7-6-17(23)13-16(18)4-3-15-5-8-19(24)25-21(15)20/h5-8,13H,2-4,9-12H2,1H3

LC determination of loratadine and related impurities
F.J. Rupe´rez, H. Ferna´ndez, C. Barbas
Journal of Pharmaceutical and Biomedical Analysis 29 (2002) 35–41
 
Measurement and Correlation of Solubility of Loratadine in Different Pure Solvents and Binary Mixtures
Xiujuan Yang,† Shui Wang,† and Jidong Wang
J. Chem. Eng. Data 2017, 62, 1, 391–397