Chemical Name: (E)-Dihydro Efavirenz ; (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one ; SR 695
Synonym: Efavirenz Ethene Analog ;
Smiles: O=C1NC2=CC=C(Cl)C=C2[C@](C(F)(F)F)(/C=C/C3CC3)O1
Inchi: InChI=1S/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1
Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections
Osnir de Sá Viana1 , Flávia Patrícia Morais Medeiros2 , Severino Grangeiro-Júnior2 , Miracy Muniz Albuquerque1 , Mônica Felts La Roca Soares1-3, José Lamartine Soares-Sobrinho1-3, Lariza Darlene Santos Alves1 , Larissa Araújo Rolim1 , Keyla Emanuelle Ramos da Silva1 , Pedro José Rolim-Neto
Braz. J. Pharm. Sci. vol.47 no.1 São Paulo Jan./Mar. 2011
Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz
Maryam A Jordaan and Michael Shapi
Antiviral Chemistry and Chemotherapy 2017: 1–11
Method Development and Validation for Related Impurities of Efavirenz by RP-HPLC Method
Desaraju Bhargavi, Bhukya Babu Rao, Gangarapu Kiran, Thumma Gouthami & Vasudha Bakshi
TACL 7 (5) 2017 pp 737 – 747